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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1H
All Species:
29.39
Human Site:
Y125
Identified Species:
53.89
UniProt:
Q9UI12
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI12
NP_057025.2
483
55883
Y125
S
K
N
T
A
W
P
Y
F
L
P
M
L
N
R
Chimpanzee
Pan troglodytes
XP_001150191
483
55912
Y125
S
K
N
T
A
W
P
Y
F
L
P
M
L
N
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544082
483
55817
Y125
S
K
N
T
A
W
S
Y
F
L
P
M
L
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVE3
483
55836
Y125
S
K
S
T
A
W
P
Y
F
L
P
M
L
N
R
Rat
Rattus norvegicus
NP_001013951
441
50841
K119
F
D
Y
A
K
R
S
K
S
T
A
W
P
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515210
483
55883
Y125
G
K
N
T
A
W
S
Y
F
L
P
M
L
N
R
Chicken
Gallus gallus
XP_423862
445
52062
Y122
G
K
N
T
A
W
S
Y
F
L
P
M
L
N
R
Frog
Xenopus laevis
NP_001089309
479
55249
Y121
G
K
N
T
A
W
S
Y
F
L
P
M
L
N
R
Zebra Danio
Brachydanio rerio
NP_775377
463
53422
Y121
T
K
N
T
A
W
S
Y
F
L
P
M
L
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J1
468
53715
P122
L
K
Q
C
I
W
G
P
F
L
N
L
L
N
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22494
470
54194
Q122
F
H
S
A
A
A
R
Q
K
R
T
V
W
S
Q
Sea Urchin
Strong. purpuratus
XP_783560
420
48731
A98
L
N
R
E
D
Q
F
A
T
T
Q
S
C
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX65
441
50266
F119
L
L
W
K
G
N
W
F
I
Q
E
K
S
C
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
N.A.
98.5
N.A.
98.5
89
N.A.
96
78
91.5
85
N.A.
52.5
N.A.
50.9
54.6
Protein Similarity:
100
98.5
N.A.
98.7
N.A.
99.3
90.2
N.A.
98.1
84.2
94.1
90
N.A.
71.8
N.A.
66.4
68.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
0
N.A.
86.6
86.6
86.6
86.6
N.A.
46.6
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
0
N.A.
86.6
86.6
86.6
93.3
N.A.
53.3
N.A.
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
70
8
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
16
0
0
0
0
0
8
8
70
0
0
0
0
0
8
% F
% Gly:
24
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
70
0
8
8
0
0
8
8
0
0
8
0
0
8
% K
% Leu:
24
8
0
0
0
0
0
0
0
70
0
8
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
62
0
0
0
% M
% Asn:
0
8
54
0
0
8
0
0
0
0
8
0
0
70
0
% N
% Pro:
0
0
0
0
0
0
24
8
0
0
62
0
8
0
0
% P
% Gln:
0
0
8
0
0
8
0
8
0
8
8
0
0
0
8
% Q
% Arg:
0
0
8
0
0
8
8
0
0
8
0
0
0
8
70
% R
% Ser:
31
0
16
0
0
0
47
0
8
0
0
8
8
8
0
% S
% Thr:
8
0
0
62
0
0
0
0
8
16
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
70
8
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _